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f480  (Cell Signaling Technology Inc)


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    Structured Review

    Cell Signaling Technology Inc f480
    a Multispectral quantitative pathology of skin abscess tissue excised from mice infected with WT, Δ cna or comp cna bacteria 3 days post inoculation and stained with antibodies targeting 6 host proteins as described in the legend. Images depict staining of entire tissue section as used for quantitative analysis. b Images digitally zoomed in (X6.5) from sections shown in ( a ). Regions of interest are depicted in a as magenta boxes. Images demonstrate staining from tissues infected with WT ( b ), Δ cna ( c ) or comp cna ( d ) and stained with antibodies targeting 6 host proteins as shown in legend. Images are separated according to channels that demonstrate spatial distribution of bacteria with collagen (DAPI, Collagen), CD45 cells, neutrophils (CD45, Ly6G) and macrophages (CD45, <t>F480).</t> e Quantification of staining demonstrated in ( a ) represented as total cells per millimeter of tissue sections infected with strains as described above. Staining of tissue was repeated for a total n = 2.
    F480, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/f480/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    f480 - by Bioz Stars, 2026-05
    86/100 stars

    Images

    1) Product Images from "Collagen binding adhesin restricts Staphylococcus aureus skin infection"

    Article Title: Collagen binding adhesin restricts Staphylococcus aureus skin infection

    Journal: Nature Communications

    doi: 10.1038/s41467-026-68788-4

    a Multispectral quantitative pathology of skin abscess tissue excised from mice infected with WT, Δ cna or comp cna bacteria 3 days post inoculation and stained with antibodies targeting 6 host proteins as described in the legend. Images depict staining of entire tissue section as used for quantitative analysis. b Images digitally zoomed in (X6.5) from sections shown in ( a ). Regions of interest are depicted in a as magenta boxes. Images demonstrate staining from tissues infected with WT ( b ), Δ cna ( c ) or comp cna ( d ) and stained with antibodies targeting 6 host proteins as shown in legend. Images are separated according to channels that demonstrate spatial distribution of bacteria with collagen (DAPI, Collagen), CD45 cells, neutrophils (CD45, Ly6G) and macrophages (CD45, F480). e Quantification of staining demonstrated in ( a ) represented as total cells per millimeter of tissue sections infected with strains as described above. Staining of tissue was repeated for a total n = 2.
    Figure Legend Snippet: a Multispectral quantitative pathology of skin abscess tissue excised from mice infected with WT, Δ cna or comp cna bacteria 3 days post inoculation and stained with antibodies targeting 6 host proteins as described in the legend. Images depict staining of entire tissue section as used for quantitative analysis. b Images digitally zoomed in (X6.5) from sections shown in ( a ). Regions of interest are depicted in a as magenta boxes. Images demonstrate staining from tissues infected with WT ( b ), Δ cna ( c ) or comp cna ( d ) and stained with antibodies targeting 6 host proteins as shown in legend. Images are separated according to channels that demonstrate spatial distribution of bacteria with collagen (DAPI, Collagen), CD45 cells, neutrophils (CD45, Ly6G) and macrophages (CD45, F480). e Quantification of staining demonstrated in ( a ) represented as total cells per millimeter of tissue sections infected with strains as described above. Staining of tissue was repeated for a total n = 2.

    Techniques Used: Infection, Bacteria, Staining



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    a Multispectral quantitative pathology of skin abscess tissue excised from mice infected with WT, Δ cna or comp cna bacteria 3 days post inoculation and stained with antibodies targeting 6 host proteins as described in the legend. Images depict staining of entire tissue section as used for quantitative analysis. b Images digitally zoomed in (X6.5) from sections shown in ( a ). Regions of interest are depicted in a as magenta boxes. Images demonstrate staining from tissues infected with WT ( b ), Δ cna ( c ) or comp cna ( d ) and stained with antibodies targeting 6 host proteins as shown in legend. Images are separated according to channels that demonstrate spatial distribution of bacteria with collagen (DAPI, Collagen), CD45 cells, neutrophils (CD45, Ly6G) and macrophages (CD45, <t>F480).</t> e Quantification of staining demonstrated in ( a ) represented as total cells per millimeter of tissue sections infected with strains as described above. Staining of tissue was repeated for a total n = 2.
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    a Multispectral quantitative pathology of skin abscess tissue excised from mice infected with WT, Δ cna or comp cna bacteria 3 days post inoculation and stained with antibodies targeting 6 host proteins as described in the legend. Images depict staining of entire tissue section as used for quantitative analysis. b Images digitally zoomed in (X6.5) from sections shown in ( a ). Regions of interest are depicted in a as magenta boxes. Images demonstrate staining from tissues infected with WT ( b ), Δ cna ( c ) or comp cna ( d ) and stained with antibodies targeting 6 host proteins as shown in legend. Images are separated according to channels that demonstrate spatial distribution of bacteria with collagen (DAPI, Collagen), CD45 cells, neutrophils (CD45, Ly6G) and macrophages (CD45, <t>F480).</t> e Quantification of staining demonstrated in ( a ) represented as total cells per millimeter of tissue sections infected with strains as described above. Staining of tissue was repeated for a total n = 2.
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    a Multispectral quantitative pathology of skin abscess tissue excised from mice infected with WT, Δ cna or comp cna bacteria 3 days post inoculation and stained with antibodies targeting 6 host proteins as described in the legend. Images depict staining of entire tissue section as used for quantitative analysis. b Images digitally zoomed in (X6.5) from sections shown in ( a ). Regions of interest are depicted in a as magenta boxes. Images demonstrate staining from tissues infected with WT ( b ), Δ cna ( c ) or comp cna ( d ) and stained with antibodies targeting 6 host proteins as shown in legend. Images are separated according to channels that demonstrate spatial distribution of bacteria with collagen (DAPI, Collagen), CD45 cells, neutrophils (CD45, Ly6G) and macrophages (CD45, <t>F480).</t> e Quantification of staining demonstrated in ( a ) represented as total cells per millimeter of tissue sections infected with strains as described above. Staining of tissue was repeated for a total n = 2.
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    Image Search Results


    a Multispectral quantitative pathology of skin abscess tissue excised from mice infected with WT, Δ cna or comp cna bacteria 3 days post inoculation and stained with antibodies targeting 6 host proteins as described in the legend. Images depict staining of entire tissue section as used for quantitative analysis. b Images digitally zoomed in (X6.5) from sections shown in ( a ). Regions of interest are depicted in a as magenta boxes. Images demonstrate staining from tissues infected with WT ( b ), Δ cna ( c ) or comp cna ( d ) and stained with antibodies targeting 6 host proteins as shown in legend. Images are separated according to channels that demonstrate spatial distribution of bacteria with collagen (DAPI, Collagen), CD45 cells, neutrophils (CD45, Ly6G) and macrophages (CD45, F480). e Quantification of staining demonstrated in ( a ) represented as total cells per millimeter of tissue sections infected with strains as described above. Staining of tissue was repeated for a total n = 2.

    Journal: Nature Communications

    Article Title: Collagen binding adhesin restricts Staphylococcus aureus skin infection

    doi: 10.1038/s41467-026-68788-4

    Figure Lengend Snippet: a Multispectral quantitative pathology of skin abscess tissue excised from mice infected with WT, Δ cna or comp cna bacteria 3 days post inoculation and stained with antibodies targeting 6 host proteins as described in the legend. Images depict staining of entire tissue section as used for quantitative analysis. b Images digitally zoomed in (X6.5) from sections shown in ( a ). Regions of interest are depicted in a as magenta boxes. Images demonstrate staining from tissues infected with WT ( b ), Δ cna ( c ) or comp cna ( d ) and stained with antibodies targeting 6 host proteins as shown in legend. Images are separated according to channels that demonstrate spatial distribution of bacteria with collagen (DAPI, Collagen), CD45 cells, neutrophils (CD45, Ly6G) and macrophages (CD45, F480). e Quantification of staining demonstrated in ( a ) represented as total cells per millimeter of tissue sections infected with strains as described above. Staining of tissue was repeated for a total n = 2.

    Article Snippet: Imaging shown includes antibodies against CD11b (1:1000 Novus, Cat No: NB110-89474), Ly6G (1:100 Cell Signaling Tech, Cat No: 87048S), COL1A1 (1:100 Cell Signaling Tech, Cat No: 72026S), CD45 (1:100 Cell Signaling Tech, Cat No: 70257S), F480 (1:100 Cell Signaling Tech, Cat No: 30325S) , .

    Techniques: Infection, Bacteria, Staining